Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Hydroxide → 3-(3,5-DI-Tert-butyl-4-hydroxy-benzyl)-pentane-2,4-dione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Acetylacetone | HCID 31261 | — |
| 반응물 | Phenol, 4-[(dimethylamino)methyl]-2,6-bis(1,1-dimethylethyl)- | HCID 66609 | — |
| 반응물 | 3-(3,5-Di-tert-butyl-4-hydroxyphenyl)pentane-2,4-dione | HCID 20455525 | — |
| 생성물 | 3-(3,5-DI-Tert-butyl-4-hydroxy-benzyl)-pentane-2,4-dione | HCID 914401 | — |
반응 단계
A mixture of N,N-dimethyl-2,6-di-t-butyl-4-aminomethylphenol (2.63 g, 10 mmols), sodium hydroxide (0.6 g, 15 mmols) and acetylacetone (24 mmols, 10% solution) was refluxed for 3 hours in a glass reaction vessel. Acetylacetone was distilled under reduced pressure to afford an oily residue containing 3-(3',5'-di-t-butyl-4'-hydroxyphenyl)-2,4-pentanedione (80% by VPC). Crystallization from ethanol:water afforded a single crop of 3-(3',5'-di-t-butyl-4'-hydroxybenzyl)-2,4-pentanedione (65%, overall yield, 97% pure).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04456770 |
| 출처 데이터셋 | uspto-grants-1984_06 |
| ORD ID | ord-d3f3aa5e645b4bd88c9e8b66867093a9 |
| 출처 메모 | uspto-grants-1984_06 |