HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 3-(3,5-DI-Tert-butyl-4-hydroxy-benzyl)-pentane-2,4-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Acetylacetone | HCID 31261 | — |
| Reactant | Phenol, 4-[(dimethylamino)methyl]-2,6-bis(1,1-dimethylethyl)- | HCID 66609 | — |
| Product | 3-(3,5-DI-Tert-butyl-4-hydroxy-benzyl)-pentane-2,4-dione | HCID 914401 | 37% |
Reaction Steps
A mixture of the N,N-dimethyl-2,6-di-t-butyl-4-aminomethylphenol (10.5 g, 40 mmols), sodium hydroxide (3.6 g, 90 mmols) and acetylacetone (24 mLs, 10% solution) was refluxed for 3 hours. Acetylacetone was distilled under reduced pressure to afford an oily residue of the 3-(3',5'-di-t-butyl-4'-hydroxybenzyl)-2,4-pentanedione compound (37% by VPC).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04456770 |
| Source dataset | uspto-grants-1984_06 |
| ORD ID | ord-ab390a976d2d49c6b3484344f63be5d4 |
| Source note | uspto-grants-1984_06 |