Ammonia → HCID 53842582, compound

HRID 1263370Notes

Reaction equation

C([S:4][CH2:5][CH2:6][C:7]([N:9]1[CH2:16][C:15]([OH:26])([CH2:17][CH2:18][CH2:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH2:14][C@H:10]1[C:11]([OH:13])=[O:12])=[O:8])(=O)C.N>>[OH:26][C:15]1([CH2:17][CH2:18][CH2:19][C:20]2[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH2:16][N:9]([C:7](=[O:8])[CH2:6][CH2:5][SH:4])[C@H:10]([C:11]([OH:13])=[O:12])[CH2:14]1

Participants

Reactant 2

HCID 222Ammonia

HCID 54239076HCID 54239076, compound

Product 1

HCID 53842582HCID 53842582, compound

Procedure

The product from part (b) is treated with concentrated ammonia according to the procedure of Example 2 to yield 4-hydroxy-1-(3-mercapto-1-oxopropyl)-4-(phenylpropyl)-L-proline.

Sources & evidence

ORD record: ord-a49b0deb80254486b050c3506080c7e7
Source dataset: uspto-grants-1984_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04456761

Reaction notes

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