2,2-Difluoropentanedioic acid → 2,2-Difluoroglutaric anhydride

Participants

Reaction Steps

A solution of 5 g of 2,2-difluoroglutaric acid in 20 ml of acetic anhydride is refluxed for two hrs, 5 ml of the resulting solution is distilled off at ordinary pressure and the residual solution freed from acetic anhydride under reduced pressure. The resulting oil consists of 2,2-difluoroglutaric anhydride.

Provenance & Evidence