反应详情

6-(2-Hydroxy-3-hexylphenyl)-6′-(2-hydroxy-3-methoxyphenyl)-2,2′-bipyridine was prepared from 6-bromo-6′-(2-hydroxy-3-methoxyphenyl)-2,2′-bipyridine and 2-hydroxy-3-hexylphenylboronic acid in 68% yield using method F; δH [2H6]-DMSO 13.23,(1H, s), 8.35,(2H, t), 8.27,(2H, m), 8.17,(1H, d), 8.10,(1H, d), 7.97,(1H, d), 7.72,(1H, d), 7.26,(1H, d), 7.09,(1H, d), 6.93,(2H, m), 3.84,(3H, s), 2.68,(2H, t), 1.62,(2H, m), 1.42-1.25(6H, m), 0.88(3H, t); MS 455 (MH)+; HPLC retention time (system 1) 4.94 minutes.

1. customHPLC retention time (system 1) 4.94 minutes