HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Phenylbenzene-1-sulfonyl chloride → N-(4-bromo-3-methyl-5-isoxazolyl)-3-biphenylsulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Phenylbenzene-1-sulfonyl chloride | HCID 3802752 | — |
| Reactant | 4-Bromo-3-methylisoxazol-5-amine | HCID 10487519 | — |
| Product | N-(4-bromo-3-methyl-5-isoxazolyl)-3-biphenylsulfonamide | HCID 15453179 | 22% |
Reaction Steps
N-(4-bromo-3-methyl-5-isoxazolyl)-3-biphenylsulfonamide was prepared in the same manner as described in Example 8b from 5-amino-4-bromo-3-methylisoxazole and 3-biphenylsulfonyl chloride in 22% yield. This was purified by HPLC (5% CH3CN to 100% CH3CN over 30 min.) to give a solid., m.p. 78-82° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06541498B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-b5861f8f3daa45d7a7ec62fbcb97d10d |
| Source note | uspto-grants-2003_04 |