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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1263748Generated: October 25, 2026

1-Amino-1,2,3,4-tetrahydronaphthalen-2-ol → 1-(N'-(3,5-Difluorophenylacetyl)-L-alaninyl)-amino-1,2,3, 4tetrahydro-2-naphthol

https://huagongshe.com/reaction/1263748

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Amino-1,2,3,4-tetrahydronaphthalen-2-olHCID 4460187—
Reactant(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoic acidHCID 12135350—
Product1-(N'-(3,5-Difluorophenylacetyl)-L-alaninyl)-amino-1,2,3, 4tetrahydro-2-naphtholHCID 54540201—

Reaction Steps

Following General Procedure C and using using N-(3,5-difluorophenylacetyl)-L-alanine (Example B) and 1-(amino-1,2,3,4-tetrahydro-2-naphthol, the title compound was prepared.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06541466B2
Source datasetuspto-grants-2003_04
ORD IDord-35bd621bee464fcaa45fed6077458704
Source noteuspto-grants-2003_04