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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1263878Generated: October 26, 2026

2-Naphthylamine → N-(2-naphthyl)alanine isobutyl ester

https://huagongshe.com/reaction/1263878

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-NaphthylamineHCID 7057—
ReactantIsobutyl pyruvateHCID 83084—
ProductN-(2-naphthyl)alanine isobutyl esterHCID 54457376—

Reaction Steps

Following General Procedure AA above and using 2-aminonaphthalene (Aldrich) and iso-butyl pyruvate (prepared by following General Procedure AO above), the title compound was prepared as an oil. Purification was by preparative plate chromatography (silica gel using 25% EtOAc/hexanes as the eluant).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06541466B2
Source datasetuspto-grants-2003_04
ORD IDord-0690bb8138e6476c96abf4c59af815bb
Source noteuspto-grants-2003_04