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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1263915Generated: November 3, 2026

2-(4-Fluorophenyl)acetic acid → 2-[(4-Fluorophenyl)acetamido]butyric acid isobutyl ester

https://huagongshe.com/reaction/1263915

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Fluorophenyl)acetic acidHCID 9837—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(4-Fluorophenyl)acetamido]butyric acid isobutyl esterHCID 54144399—

Reaction Steps

Following General Procedure BI above and using 4-fluorophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06541466B2
Source datasetuspto-grants-2003_04
ORD IDord-55cbef126a2046f9b89e9317974abe35
Source noteuspto-grants-2003_04