Sulfanilamide Hydrochloride → HCID 178514726, compound

HRID 1263977Notes

Reaction equation

C(O[CH:4]=[C:5]1[C:13]2[C:8](=[CH:9][CH:10]=[C:11]([C:14]3[O:18][CH:17]=[N:16][CH:15]=3)[CH:12]=2)[NH:7][C:6]1=[O:19])C.Cl.[NH2:21][C:22]1[CH:27]=[CH:26][C:25]([S:28]([NH2:31])(=[O:30])=[O:29])=[CH:24][CH:23]=1>>[O:18]1[C:14]([C:11]2[CH:12]=[C:13]3[C:8](=[CH:9][CH:10]=2)[NH:7][C:6](=[O:19])[C:5]3=[CH:4][NH:21][C:22]2[CH:27]=[CH:26][C:25]([S:28]([NH2:31])(=[O:29])=[O:30])=[CH:24][CH:23]=2)=[CH:15][N:16]=[CH:17]1

Participants

Reactant 2

HCID 80197Sulfanilamide Hydrochloride

HCID 53832760Ethoxymethylene-5-oxazol-5-yl-1,3-dihydro-indol-2-one

Product 1

HCID 178514726HCID 178514726, compoundYield 68%

Procedure

The title compound was prepared in 68% yield from ethoxymethylene-5-oxazol-5-yl-1,3-dihydro-indol-2-one and 4-aminobenzenesulfonamide hydrochloride according to Procedure J: 1H NMR (DMSO-6): δ 10.79 (d,1H), 10.73 (s, 1H), 8.76 (d, 1H), 8.38 (s, 1H), 8.0 ( s, 1H), 7.77 (d, 2H), 7.56 ( d, 2H), 7.43 (s, 1H), 7.40 (d, 1H), 7.26 (s, 2H), 6.91 (d, 1H); APCI−MS: m/z 381 (MH)−.

Sources & evidence

ORD record: ord-245bc8b435a84137a07a45869959c6b8
Source dataset: uspto-grants-2003_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06541503B2

Reaction notes

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