1-Propanol, 3-amino-2,2-dimethyl- → HCID 178450602, compound

HRID 1263992Notes

Reaction equation

HRID 1263992 reaction equation
FC1C(O[C:9]([C:11]2[CH:12]=[C:13]3[C:17](=[CH:18][CH:19]=2)[NH:16][C:15](=[O:20])[C:14]3=[N:21][NH:22][C:23]2[CH:28]=[CH:27][C:26]([S:29](=[O:32])(=[O:31])[NH2:30])=[CH:25][CH:24]=2)=[O:10])=C(F)C(F)=C(F)C=1F.[OH:37][CH2:38][C:39]([CH3:43])([CH3:42])[CH2:40][NH2:41]>>[OH:37][CH2:38][C:39]([CH3:43])([CH3:42])[CH2:40][NH:41][C:9]([C:11]1[CH:12]=[C:13]2[C:17](=[CH:18][CH:19]=1)[NH:16][C:15](=[O:20])[C:14]2=[N:21][NH:22][C:23]1[CH:28]=[CH:27][C:26]([S:29](=[O:32])(=[O:31])[NH2:30])=[CH:25][CH:24]=1)=[O:10]

Participants

3

Reactant 2

HCID 1173261-Propanol, 3-amino-2,2-dimethyl-HCID 178514750HCID 178514750, compound

Product 1

HCID 178450602HCID 178450602, compound

Procedure

The title compound was prepared from 2-oxo-3[(4-sulfamoyl-phenyl)-hydrazono]-2,3-dihydro-1H-indole-5-carboxylic acid pentafluorophenyl ester and 3-hydroxy-2,2-dimethylpropylamine according to Procedure K: mp>230° C.; Anal. Calcd for C20H23N5O5S: C, 53.92; H, 5.20; N, 15.72. Found: C, 54.04; H, 5.17; N, 15.77.

Sources & evidence

ORD record
ord-f494f70c0f7b4c3684908c088eb6b4c2
Source dataset
uspto-grants-2003_04
Patent number
US06541503B2

Reaction notes

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