HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Fluorobenzoyl chloride → HCID 10267793, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Fluorobenzoyl chloride | HCID 74376 | — |
| Reactant | Methyl 4-(4-aminophenyl)-4-oxobutanoate | HCID 12016833 | — |
| Product | HCID 10267793 | HCID 10267793 | 42% |
Reaction Steps
In a manner similar to that described in Example 3, 3-fluorobenzoyl chloride (0.053 g, 0.00033 mol) was allowed to react with 4-(4-amino-phenyl)-4-oxo-butyric acid, methyl ester (0.052 g, 0.00025 mol) (Example 1, Step (c)), and the resulting intermediate was hydrolyzed to give 0.0331 g of 4-[4-(3-fluoro-benzoylamino)-phenyl]-4-oxo-butyric acid as an off-white solid; mp 239-241° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06541521B1 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-cd7470b6f440433dbe079b32f900df8d |
| Source note | uspto-grants-2003_04 |