HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluorobenzoyl chloride → HCID 10308548, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluorobenzoyl chloride | HCID 9808 | — |
| Reactant | Methyl 4-(4-aminophenyl)-4-oxobutanoate | HCID 12016833 | — |
| Product | HCID 10308548 | HCID 10308548 | 55.6% |
Reaction Steps
In a manner similar to that described in Example 3, 2-fluorobenzoyl chloride (0.053 g, 0.00033 mol) was allowed to react with 4-(4-amino-phenyl)-4-oxo-butyric acid, methyl ester (0.052 g, 0.00025 mol) (Example 1, Step (c)), and the resulting intermediate was hydrolyzed to give 0.0438 g of 4-[4-(2-fluoro-benzoylamino)-phenyl]-4-oxo-butyric acid as an off-white solid; mp 191-193° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06541521B1 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-6c5fffe568cd447e995e52fca596c75a |
| Source note | uspto-grants-2003_04 |