HuagongsheHuagongshe Chemistry Print Report · For research reference only
Heptanoyl chloride → 4-[4-(Heptanoylamino)-phenyl]-4-oxo-butyric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Heptanoyl chloride | HCID 17313 | — |
| Reactant | Methyl 4-(4-aminophenyl)-4-oxobutanoate | HCID 12016833 | — |
| Product | 4-[4-(Heptanoylamino)-phenyl]-4-oxo-butyric acid | HCID 9922530 | 62.9% |
Reaction Steps
In a manner similar to that described in Example 3, heptanoyl chloride (0.051 g, 0.00034 mol) was allowed to react with 4-(4-amino-phenyl)-4-oxo-butyric acid, methyl ester (0.052 g, 0.00025 mol), and the resulting intermediate was hydrolyzed to give 0.048 g of 4-[4-(heptanoylamino)-phenyl]-4-oxo-butyric acid as an off-white solid; MS-(AP+) MH+306.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06541521B1 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-0be7469252384cb1882b5a95deaffdcd |
| Source note | uspto-grants-2003_04 |