HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Difluorobenzoyl chloride → HCID 9923695, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Difluorobenzoyl chloride | HCID 588081 | — |
| Reactant | Methyl 4-(4-aminophenyl)-4-oxobutanoate | HCID 12016833 | — |
| Product | HCID 9923695 | HCID 9923695 | 76.8% |
Reaction Steps
In a manner similar to that described in Example 3, 2,4-difluoro-benzoyl chloride (0.059 g, 0.00033 mol) was allowed to react with 4-(4-amino-phenyl)-4-oxo-butyric acid, methyl ester (0.052 g, 0.00025 mol), and the resulting intermediate was hydrolyzed to give 0.064 g of 4-[4-(2,4-difluoro-benzoylamino)-phenyl]-4-oxo-butyric acid as an off-white solid; MS-(AP+) MH+334.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06541521B1 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-5f06f05cd498425fba4d8442b1792736 |
| Source note | uspto-grants-2003_04 |