Triacetoxyperiodinane → HCID 18617539, compound

Participants

Reaction Steps

To a solution of 2-(4-furan-2-yl-phenyl)-2-methyl-propan-1-ol (6.56 g, 30 mmol) (reference example 53) in CH2Cl2 (200 mL) is added Dess-Martin periodinane (22.5 g, 53 mmol) and the resulting mixture stirred for 45 min then concentrated. The residue is purified by flash chromatography (eluting with 10% ethyl acetate in hexanes) to give 5.64 g of title compound. 1H NMR (CDCl3) δ 1.48 (s, 6H), 6.47 (m, 1H), 6.66 (d, J=3 Hz, 1H), 7.30 (d, J=8 Hz, 2H), 7.46 (s, 1H), 7.68 (d, J=8 Hz, 2H), 9.50 (s, 1H). MS (EI) m/z 214 (M+).

Provenance & Evidence