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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1264269Generated: November 2, 2026

4-(Methylamino)butyric acid → 4-[(4-{4-[2-(3-Cyano-1H-indol-5-yl)ethylcarbamoyl]phenyl}pyrimidin-2-yl)methylamino]-butyric acid

https://huagongshe.com/reaction/1264269

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Methylamino)butyric acidHCID 70703—
ReactantN-[2-(3-Cyano-1H-indol-5-yl)-ethyl]-4-[2-chloropyrimidin-4-yl]benzamideHCID 18617562—
Product4-[(4-{4-[2-(3-Cyano-1H-indol-5-yl)ethylcarbamoyl]phenyl}pyrimidin-2-yl)methylamino]-butyric acidHCID 18617658—

Reaction Steps

Using 4-(methylamino)-butyric acid and N-[2-(3-Cyano-1H-indol-5-yl)-ethyl]-4-[2-chloro-pyrimidin-4-yl]-benzamide (reference example 1az) as substrates. MS (ion spray) m/z 483 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06541505B1
Source datasetuspto-grants-2003_04
ORD IDord-dbead1c45700471eaffec7ee2c2a730a
Source noteuspto-grants-2003_04