2-(Methylamino)ethanol → HCID 18617730, compound

HRID 1264281Notes

Reaction equation

HRID 1264281 reaction equation
[OH:1][CH2:2][CH2:3][NH:4][CH3:5].[C:6]([C:8]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14]([CH2:17][CH2:18][NH:19][C:20](=[O:34])[C:21]3[CH:26]=[CH:25][C:24]([C:27]4[CH:32]=[CH:31][N:30]=[C:29](Cl)[N:28]=4)=[CH:23][CH:22]=3)[CH:15]=2)[NH:10][CH:9]=1)#[N:7]>>[C:6]([C:8]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14]([CH2:17][CH2:18][NH:19][C:20](=[O:34])[C:21]3[CH:26]=[CH:25][C:24]([C:27]4[CH:32]=[CH:31][N:30]=[C:29]([N:4]([CH2:3][CH2:2][OH:1])[CH3:5])[N:28]=4)=[CH:23][CH:22]=3)[CH:15]=2)[NH:10][CH:9]=1)#[N:7]

Participants

3

Reactant 2

HCID 80162-(Methylamino)ethanolHCID 18617562N-[2-(3-Cyano-1H-indol-5-yl)-ethyl]-4-[2-chloropyrimidin-4-yl]benzamide

Product 1

HCID 18617730HCID 18617730, compound

Procedure

Using (2-hydroxy-ethyl)-N-methylamine and N-[2-(3-Cyano-1H-indol-5-yl)-ethyl]-4-[2-chloro-pyrimidin-4-yl]-benzamide (reference example 1az) as substrates. MS (ion spray) m/z 441 (M+H)+.

Sources & evidence

ORD record
ord-bb0ee8f840cb460abb1a4e05d0a79016
Source dataset
uspto-grants-2003_04
Patent number
US06541505B1

Reaction notes

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