Morpholine → HCID 18617636, compound

Participants

Role	Name	HCID	Charge
Reactant	Morpholine	HCID 8083	—
Reactant	N-[2-(3-Cyano-1H-indol-5-yl)-ethyl]-4-[2-chloropyrimidin-4-yl]benzamide	HCID 18617562	—
Product	HCID 18617636	HCID 18617636	—

Reaction Steps

Using morpholine and N-[2-(3-Cyano-1H-indol-5-yl)-ethyl]-4-[2-chloro-pyrimidin-4-yl]-benzamide (reference example 1az) as substrates. 1H NMR (DMSO) δ 2.98 (bt, 2H, J=7 Hz); 3.56 (m, 2H); 3.70 (bs, 4H); 3.79 (bs, 4H); 7.18 (d, 1H, J=9 Hz); 7.32 (d, 1H, J=5 Hz); 7.49 (m, 2H); 7.94 (d, 2H, J=8 Hz); 8.22 (m, 3H); 8.50 (d, 1H, J=5 Hz); 8.74 (bt, 1H); 12.20 (bs, 1H). MS (ion spray) m/z 453 (M+H)+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06541505B1
Source dataset	uspto-grants-2003_04
ORD ID	ord-d2a30aee205f44cb894db1821703ce39
Source note	uspto-grants-2003_04