3-Amino-1-propanol → HCID 70030618, compound

Participants

Role	Name	HCID	Charge
Reactant	3-Amino-1-propanol	HCID 9086	—
Reactant	N-[2-(3-Cyano-1H-indol-5-yl)-ethyl]-4-[2-chloropyrimidin-4-yl]benzamide	HCID 18617562	—
Product	HCID 70030618	HCID 70030618	—

Reaction Steps

Using 3-hydroxy-propylamine and N-[2-(3-Cyano-1H-indol-5-yl)-ethyl]-4-[2-chloro-pyrimidin-4-yl]-benzamide (reference example 1az) as substrates. 1H NMR (DMSO) δ 1.73 (t, 2H, J=7 Hz); 2.98 (t, 2H, J=7 Hz); 3.40 (m, 2H); 4.48 (bs, 1H); 7.20 (m, 3H); 7.48 (m, 2H); 7.92 (d, 2H, J=8 Hz); 8.18 (m, 3H); 8.37 (bd, 1H, J=5 Hz); 8.68 (bt, 1H); 12.12 (bs, 1H). MS (ion spray) m/z 441 (M+H)+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06541505B1
Source dataset	uspto-grants-2003_04
ORD ID	ord-c9b31d57dcb142669bebcab0be375632
Source note	uspto-grants-2003_04