3-(Methylamino)propane-1,2-diol → HCID 18617763, compound

HRID 1264290Notes

Reaction equation

HRID 1264290 reaction equation
[OH:1][CH:2]([CH2:6][OH:7])[CH2:3][NH:4][CH3:5].[C:8]([C:10]1[C:18]2[C:13](=[CH:14][CH:15]=[C:16]([CH2:19][CH2:20][NH:21][C:22](=[O:36])[C:23]3[CH:28]=[CH:27][C:26]([C:29]4[CH:34]=[CH:33][N:32]=[C:31](Cl)[N:30]=4)=[CH:25][CH:24]=3)[CH:17]=2)[NH:12][CH:11]=1)#[N:9]>>[C:8]([C:10]1[C:18]2[C:13](=[CH:14][CH:15]=[C:16]([CH2:19][CH2:20][NH:21][C:22](=[O:36])[C:23]3[CH:28]=[CH:27][C:26]([C:29]4[CH:34]=[CH:33][N:32]=[C:31]([N:4]([CH2:3][CH:2]([OH:1])[CH2:6][OH:7])[CH3:5])[N:30]=4)=[CH:25][CH:24]=3)[CH:17]=2)[NH:12][CH:11]=1)#[N:9]

Participants

3

Reactant 2

HCID 27341223-(Methylamino)propane-1,2-diolHCID 18617562N-[2-(3-Cyano-1H-indol-5-yl)-ethyl]-4-[2-chloropyrimidin-4-yl]benzamide

Product 1

HCID 18617763HCID 18617763, compound

Procedure

Using 2,3-dihydroxy-propyl-methylamine and N-[2-(3-Cyano-1H-indol-5-yl)-ethyl]-4-[2-chloro-pyrimidin-4-yl]-benzamide (reference example 1az) as substrates. MS (ion spray) m/z 471 (M+H)+.

Sources & evidence

ORD record
ord-b36762f505c0493a95fbf601b29d55de
Source dataset
uspto-grants-2003_04
Patent number
US06541505B1

Reaction notes

Loading…