Benzocaine → HCID 11459007, compound

HRID 1264387Notes

Reaction equation

HRID 1264387 reaction equation
[NH:1](C(OCC1C=CC=CC=1)=O)[CH2:2][CH2:3][C:4](O)=[O:5].[CH2:17]([O:19][C:20](=[O:28])[C:21]1[CH:26]=[CH:25][C:24]([NH2:27])=[CH:23][CH:22]=1)[CH3:18]>>[CH2:17]([O:19][C:20](=[O:28])[C:21]1[CH:26]=[CH:25][C:24]([NH:27][C:4](=[O:5])[CH2:3][CH2:2][NH2:1])=[CH:23][CH:22]=1)[CH3:18]

Participants

3

Reactant 2

HCID 2337BenzocaineHCID 75313N-Benzyloxycarbonyl-beta-alanine

Product 1

HCID 11459007HCID 11459007, compound

Procedure

Z-beta-Ala-OH and ethyl-4-aminobenzoate according to 1.2., followed by deprotection according to 6.1. to give 4-(3-Amino-propionylamino)-benzoic acid ethyl ester, MS: 236 (M).

Sources & evidence

ORD record
ord-d40431d87cc349e7805421ae6caaeaba
Source dataset
uspto-grants-2003_04
Patent number
US06541638B2

Reaction notes

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