2-Amino-5-hydroxybenzotrifluoride → 6-(cyclohexylamino)-N-(4-hydroxy-2-(trifluoromethyl)phenyl)pyrimidine-4-carboxamide

HRID 126440Notes

Reaction equation

HRID 126440 reaction equation
[CH:1]1([NH:7][c:8]2[cH:9][c:10]([C:14](=[O:15])[OH:16])[n:11][cH:12][n:13]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[NH2:17][c:18]1[c:19]([C:25]([F:26])([F:27])[F:28])[cH:20][c:21]([OH:24])[cH:22][cH:23]1>>[CH:1]1([NH:7][c:8]2[cH:9][c:10]([C:14](=[O:16])[NH:17][c:18]3[c:19]([C:25]([F:26])([F:27])[F:28])[cH:20][c:21]([OH:24])[cH:22][cH:23]3)[n:11][cH:12][n:13]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 146928342-Amino-5-hydroxybenzotrifluorideHCID 594470756-(Cyclohexylamino)pyrimidine-4-carboxylic acid

Product 1

HCID 251827536-(cyclohexylamino)-N-(4-hydroxy-2-(trifluoromethyl)phenyl)pyrimidine-4-carboxamide

Sources & evidence

ORD record
ord-8ae3764fb3ca4a0590a0587e16ac6fc4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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