HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoic acid → HCID 10225418, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoic acid | HCID 12135350 | — |
| Reactant | HCID 22312448 | HCID 22312448 | — |
| Solvent | Chloroform methanol | HCID 21584188 | — |
| Product | HCID 10225418 | HCID 10225418 | — |
Reaction Steps
Following General Procedure D and using N-(3,5-difluorophenylacetyl)-L-alanine (Ex. B) and 5-amino-3,3,7-trimethyl-5,7-dihydro-6H-benz[b]azepin-6-one hydrochloride (Example 6-C), the title compound was prepared. The reaction was monitored by tlc (Rf=0.4, 5% MeOH/CHCl3) and product was purified by chromatography (silica, 5% MeOH/CHCl3) and crystallization from acetonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06544978B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-a22f71cbada44a79af10daf7dc82a038 |
| Source note | uspto-grants-2003_04 |