HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylacetyl chloride → N-(phenylacetyl)-D,L-alanine iso-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylacetyl chloride | HCID 7679 | — |
| Reactant | 2-Methylpropyl (2S)-2-aminopropanoate hydrochloride | HCID 86584981 | — |
| Product | N-(phenylacetyl)-D,L-alanine iso-butyl ester | HCID 9903374 | — |
Reaction Steps
Following General Procedure BA above and using phenylacetyl chloride (Aldrich) and D, L-alanine iso-butyl ester hydrochloride (from Example BB above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by extraction with Et2O followed by washes with aqueous K2CO3 and aqueous HCl.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06544978B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-0a708e7d93ec484dad834be9a514f0a6 |
| Source note | uspto-grants-2003_04 |