Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1264837Generated: October 31, 2026

Benzeneacetic acid, 2-fluoro- → 2-[(2-fluorophenyl)acetamido]butyric Acid Iso-butyl Ester

https://huagongshe.com/reaction/1264837

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzeneacetic acid, 2-fluoro-HCID 67979—
ReactantIsobutyl 2-aminobutyrateHCID 13743360—
Product2-[(2-fluorophenyl)acetamido]butyric Acid Iso-butyl EsterHCID 53643249—

Reaction Steps

Following General Procedure BI above and using 2-fluorophenylacetic acid (Aldrich) and iso-butyl 2-aminobutyrate (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06544978B2
Source datasetuspto-grants-2003_04
ORD IDord-cbe42321922c414fa3119e458c511a78
Source noteuspto-grants-2003_04