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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1264853Generated: October 31, 2026

3-Thiophenacetic acid → N-[(3thienyl)acetyl]alanine Iso-butyl Ester

https://huagongshe.com/reaction/1264853

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Thiophenacetic acidHCID 23404—
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
ProductN-[(3thienyl)acetyl]alanine Iso-butyl EsterHCID 53969374—

Reaction Steps

Following General Procedure BI above, and using 3-thiopheneacetic acid (Aldrich) and alanine iso-butyl ester (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06544978B2
Source datasetuspto-grants-2003_04
ORD IDord-40b5c421a1d24307830c6a6afacb293a
Source noteuspto-grants-2003_04