HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-4'-(trifluoromethyl)acetophenone → Methyl 4-[4-(4-trifluoromethylphenyl)-2-thiazoly]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-4'-(trifluoromethyl)acetophenone | HCID 321979 | — |
| Reactant | Methyl 4-carbamothioylbenzoate | HCID 11401319 | — |
| Product | Methyl 4-[4-(4-trifluoromethylphenyl)-2-thiazoly]benzoate | HCID 18613810 | 61% |
Reaction Steps
In the same manner as in Example 28, methyl 4-thiocarbamoylbenzoate was reacted with 4-trifluoromethylphenacyl bromide to obtain methyl 4-[4-(4-trifluoromethylphenyl)-2-thiazoly]benzoate. The product was recrystallized from ethanol. Yield: 61%. Colorless prisms. Melting point: 156 to 158° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06545009B1 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-3ccb53a005f7488ca93a8e00fa731c18 |
| Source note | uspto-grants-2003_04 |