HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-1-(4-(propan-2-yl)phenyl)ethan-1-one → Ethyl 3-[4-(4-isopropylphenyl)thiazol-2-yl]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-1-(4-(propan-2-yl)phenyl)ethan-1-one | HCID 14042756 | — |
| Reactant | Ethyl 3-thiocarbamoylbenzoate | HCID 18613909 | — |
| Product | Ethyl 3-[4-(4-isopropylphenyl)thiazol-2-yl]benzoate | HCID 18613855 | 46% |
Reaction Steps
In the same manner as in Example 74, ethyl 3-thiocarbamoylbenzoate was reacted with 4-isopropylphenacyl bromide to obtain ethyl 3-[4-(4-isopropylphenyl)-2-thiazolyl]benzoate. The product was recrystallized from ethanol. Yield: 46%. Pale yellow prisms. Melting point: 91 to 92° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06545009B1 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-98a95cdbdd0a4a2ba91936ebd9cfea38 |
| Source note | uspto-grants-2003_04 |