HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Pyridinecarbothioamide → Ethyl 4-[2-(4-pyridyl)-4-thiazolyl)benzoate hydrobromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Pyridinecarbothioamide | HCID 2723788 | — |
| Reactant | Ethyl 4-(2-bromoacetyl)benzoate | HCID 11966043 | — |
| Product | Ethyl 4-[2-(4-pyridyl)-4-thiazolyl)benzoate hydrobromide | HCID 18613814 | 67% |
Reaction Steps
In the same manner as in Example 74, thioisonicotinamide was reacted with ethyl 4-bromoacetylbenzoate to obtain ethyl 4-[2-(4-pyridyl)-4-thiazolyl)benzoate hydrobromide. The product was, recrystallized from ethanol. Yield: 67%. Pale Yellow prisms. Melting point: 247 to 248° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06545009B1 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-2112c5fbc84a471482d1dcee802a2480 |
| Source note | uspto-grants-2003_04 |