3-Phenylpropylamine → HCID 10178367, compound

HRID 1264972Notes

Reaction equation

HRID 1264972 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([NH:7][S:8]([N:11]2[CH2:15][CH2:14][CH2:13][C@H:12]2[C:16]([OH:18])=O)(=[O:10])=[O:9])[CH:2]=1.[C:19]1([CH2:25][CH2:26][CH2:27][NH2:28])[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[C:19]1([CH2:25][CH2:26][CH2:27][NH:28][C:16]([C@@H:12]2[CH2:13][CH2:14][CH2:15][N:11]2[S:8](=[O:9])(=[O:10])[NH:7][C:3]2[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=2)=[O:18])[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

Participants

3

Reactant 2

HCID 162593-PhenylpropylamineHCID 9835184HCID 9835184, compound

Product 1

HCID 10178367HCID 10178367, compound

Procedure

Compound 118 was prepared from the carboxylic acid (compound 116) and 3-phenyl-propylamine by a synthetic method analogous to the step 2 of compound 31 synthesis. A 21% yield was obtained for the title compound.

Sources & evidence

ORD record
ord-d674ff21047b4658a72eb4676be51e13
Source dataset
uspto-grants-2003_04
Patent number
US06544987B2

Reaction notes

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