2-Furoyl isothiocyanate → N-[(4-{2-[4-amino-2-(ethoxymethyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl]ethyl}piperidin-1-yl)carbonothioyl]-2-furamide

Participants

Role	Name	HCID	Charge
Reactant	2-Furoyl isothiocyanate	HCID 2759243	—
Reactant	2-(ethoxymethyl)-6,7-dimethyl-1-(2-piperidin-4-ylethyl)-1H-imidazo[4,5-c]pyridin-4-amine	HCID 12972962	—
Product	N-[(4-{2-[4-amino-2-(ethoxymethyl)-6,7-dimethyl-1H-imidazo[4,5-c]pyridin-1-yl]ethyl}piperidin-1-yl)carbonothioyl]-2-furamide	HCID 22397368	—

Reaction Steps

Using the method of Examples 54-65, 2-furoylisothiocyanate was reacted with 2-(ethoxymethyl)-6,7-dimethyl-1-(2-piperidin-4-ylethyl)-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired compound. The observed accurate mass was 485.2357.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06545017B1
Source dataset	uspto-grants-2003_04
ORD ID	ord-f1914aa01d5e45c8adb0d5d3870037a5
Source note	uspto-grants-2003_04