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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1265087Generated: October 26, 2026

trans-2-Phenylcyclopropyl isocyanate → N-[3-(4-amino-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-1-yl)propyl]-N'-[(1R*,2S)-2-phenylcyclopropyl]urea

https://huagongshe.com/reaction/1265087

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttrans-2-Phenylcyclopropyl isocyanateHCID 255285—
Reactant1-(3-aminopropyl)-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-4-amineHCID 21946031—
ProductN-[3-(4-amino-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-1-yl)propyl]-N'-[(1R*,2S)-2-phenylcyclopropyl]ureaHCID 20575809—

Reaction Steps

Using the methods of Examples 75-85, trans-2-phenylcyclopropyl isocyanate was reacted with 1-(3-aminopropyl)-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired compound. The observed accurate mass was 393.2393.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06545017B1
Source datasetuspto-grants-2003_04
ORD IDord-7db57db69f5b45679a5a907e5e747ce1
Source noteuspto-grants-2003_04