m-Chloroperbenzoic acid → HCID 9801756, compound

Participants

Reaction Steps

To a solution of acetamide (2) (145 mg, 0.37 mmol) in CH2Cl2 (5 mL), m-CPBA (500 mg) was added. The reaction mixture was stirred at room temperature for 30 min. and aq. NaHCO3 (10 mL) was added and the organic layer separated and washed with water (2×10 mL), dried (Na2SO4) and concentrated to obtain the title compound as a white solid. (35%); 1H NMR (CDCl3) δ 7.8 (2H, m), 4.33 and 4.46 (2H each, m), 2.12 (3H, s); MS (M+) 428.

Provenance & Evidence