4-Amino-8-bromo-N-propylcinnoline-3-carboxamide → 4-amino-8-(5-fluoro-6-methoxy-3-pyridyl)-N-propyl-cinnoline-3-carboxamide
Reaction equation
[F:19][c:20]1[cH:21][c:22]([B:28]([OH:29])[OH:30])[cH:23][n:24][c:25]1[O:26][CH3:27].[NH2:1][c:2]1[c:3]([C:13](=[O:14])[NH:15][CH2:16][CH2:17][CH3:18])[n:4][n:5][c:6]2[c:7]([Br:12])[cH:8][cH:9][cH:10][c:11]12>>[NH2:1][c:2]1[c:3]([C:13](=[O:14])[NH:15][CH2:16][CH2:17][CH3:18])[n:4][n:5][c:6]2[c:7](-[c:22]3[cH:21][c:20]([F:19])[c:25]([O:26][CH3:27])[n:24][cH:23]3)[cH:8][cH:9][cH:10][c:11]12Participants
3
Sources & evidence
- ORD record
- ord-2a4d5a5d863d4eae9a6b34cc72080cea
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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