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HRID1265352

反应详情

EQUATION

反应方程式

HRID 1265352 的结构方程式

REACTANTS

反应物

2
结构：O=[N+]([O-])O
HCID944

Nitric Acid

HNO3

结构：Cn1c(C(F)(F)F)cc(=O)n(-c2cc(O)c(Cl)cc2F)c1=O
HCID11267757

未命名化合物

PRODUCTS

生成物

1
结构：Cn1c(C(F)(F)F)cc(=O)n(-c2c(F)cc(Cl)c(O)c2[N+](=O)[O-])c1=O
HCID18315086

未命名化合物

PROCEDURE

实验过程

3-(4-Chloro-2-fluoro-5-hydroxyphenyl)-1-methyl-6-trifluoromethyl-2,4(1H, 3H)-pyrimidinedione (1.06 g) was added to ice-cold con. nitric acid (10 ml). After stirring for 30 min, crushed ice was added. The yellow crystals were collected by filtration to afford the title compound (1.2 g).

WORKUP

后处理

  1. customcrushed ice
  2. additionwas added
  3. filtrationThe yellow crystals were collected by filtration