HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Butanol → HCID 21349844, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Butanol | HCID 263 | — |
| Reactant | Diphosgene | HCID 10426 | — |
| Reactant | Isocyanate | HCID 105034 | — |
| Reactant | 5-Chloro-4-iodo-2-nitroaniline | HCID 22317548 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 21349844 | HCID 21349844 | — |
Reaction Steps
The title compound was prepared via the isocyanate from 5-chloro-4-iodo-2-nitro-phenylamine (Example A1) (7.0 g, 23.45 mmol) with diphosgene (2.12 mL, 17.6 mmol) in EtOAc (30 mL), followed by treatment with tert.-BuOH (100 mL) in CH2Cl2 (100 mL) according to the general procedure B (method a). Obtained as a yellow solid (7.1 g, 76%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06544985B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-75401268565f4f508b3d460a24b595b8 |
| Source note | uspto-grants-2003_04 |