Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pyrrolidine → (2-Nitro-5-pyrrolidin-1-yl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pyrrolidine | HCID 31268 | — |
| 반응물 | (5-Chloro-2-nitro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester | HCID 69489376 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 생성물 | (2-Nitro-5-pyrrolidin-1-yl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester | HCID 69486800 | — |
반응 단계
The title compound was prepared from (5-chloro-2-nitro-4-trifluoromethyl-phenyl)-carbamic acid tert.-butyl ester (Example B5) (6.81 g, 20 mmol) and pyrrolidine (8.27 mL, 100 mmol) in DMSO (70 mL) at 23° C. according to the general procedure C. Obtained as a yellow solid (7.35 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06544985B2 |
| 출처 데이터셋 | uspto-grants-2003_04 |
| ORD ID | ord-4c28f7ef57d042589a71cf45ca011ead |
| 출처 메모 | uspto-grants-2003_04 |