HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → (2-Dimethylamino-2'-fluoro-5-nitro-biphenyl-4-yl)-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | HCID 69486785 | HCID 69486785 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | (2-Dimethylamino-2'-fluoro-5-nitro-biphenyl-4-yl)-carbamic acid tert-butyl ester | HCID 69489429 | — |
Reaction Steps
The title compound was prepared from (2-chloro-2′-fluoro-5-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester (Example D3) (9.568 g, ca. 26 mmol) and Me2NH (60% in H2O, 12 mL) in DMSO (87 mL) at 23° C. according to the general procedure C. Obtained as a yellow solid (4.54 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06544985B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-9d85893fbd234047be7c5dc8396683df |
| Source note | uspto-grants-2003_04 |