HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → HCID 69688410, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | 4-(Boc-amino)-2-fluoro-5-nitrobenzonitrile | HCID 69687274 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 69688410 | HCID 69688410 | — |
Reaction Steps
The title compound was prepared from (4-cyano-5-fluoro-2-nitro-phenyl)-carbamic acid tert-butyl ester (Example B9) (2.0 g, 7.11 mmol) and dimethylamine (6.3 ml, 33% in EtOH, 35.0 mmol) in DMSO (30 mL) at RT according to the general procedure C. Obtained as a yellow solid (1.87 g, 86%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06544985B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-89f2bc02a1594784b0f183c5ed366f6b |
| Source note | uspto-grants-2003_04 |