HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutylamine → (5-Isobutylamino-2-nitro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutylamine | HCID 6558 | — |
| Reactant | (5-Chloro-2-nitro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester | HCID 69489376 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | (5-Isobutylamino-2-nitro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester | HCID 17953218 | — |
Reaction Steps
The title compound was prepared from (5-chloro-2-nitro-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example B5) (5.00 g, 14.7 mmol), isobutyl-amine (7.36 mL, 73.4 mmol) in DMSO (35 mL) at RT according to the general procedure C. Obtained as a yellow solid (5.39 g, 97%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06544985B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-0b5053dd7b254feda0eeb564a1cefc4c |
| Source note | uspto-grants-2003_04 |