HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(2-Nitro-5-pyrrolidin-1-yl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester → (2-Amino-5-pyrrolidin-1-yl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (2-Nitro-5-pyrrolidin-1-yl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester | HCID 69486800 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Produkt | (2-Amino-5-pyrrolidin-1-yl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester | HCID 69489422 | — |
Reaktionsschritte
The title compound was prepared from (2-nitro-5-pyrrolidin-1-yl-4-trifluoromethyl-phenyl)-carbamic acid tert.-butyl ester (Example C10) (7.35 g, 19.75 mmol) by hydrogenation with 10% Pd/C according to the general procedure J (method a). Obtained as a light orange solid (6.75 g).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06544985B2 |
| Quelldatensatz | uspto-grants-2003_04 |
| ORD ID | ord-c00ee0904785438db5cdfaf0632a2bd9 |
| Quellennotiz | uspto-grants-2003_04 |