HuagongsheHuagongshe Chemistry Print Report · For research reference only
(5-Dimethylamino-4-fluoro-2-nitro-phenyl)-carbamic acid tert.-butyl ester → (2-Amino-5-dimethylamino-4-fluoro-phenyl)-carbamic acid tert.-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (5-Dimethylamino-4-fluoro-2-nitro-phenyl)-carbamic acid tert.-butyl ester | HCID 69688435 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | (2-Amino-5-dimethylamino-4-fluoro-phenyl)-carbamic acid tert.-butyl ester | HCID 69688174 | — |
Reaction Steps
The title compound was prepared from (5-dimethylamino-4-fluoro-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example C11) (4.88 g, 16 mmol) by hydrogenation with 10% Pd/C according to the general procedure J (method a). Obtained as a green solid (4.55 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06544985B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-1e9cfaaf08964802aade67834786209e |
| Source note | uspto-grants-2003_04 |