HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Stannous chloride dihydrate → [2-Amino-5-(cyclopropyl-methyl-amino)-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Stannous chloride dihydrate | HCID 61436 | — |
| Edukt | [5-(Cyclopropyl-methyl-amino)-2-nitro-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester | HCID 69486640 | — |
| Produkt | [2-Amino-5-(cyclopropyl-methyl-amino)-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester | HCID 69489708 | — |
Reaktionsschritte
The title compound was prepared from [5-(cyclopropyl-methyl-amino)-2-nitro-4-trifluoromethyl-phenyl]-carbamic acid tert.-butyl ester (Example C17) (3.74 g, 9.96 mmol) by reduction with SnCl2.2H2O according to the general procedure J (method b). Obtained as an orange semisolid (2.00 g).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06544985B2 |
| Quelldatensatz | uspto-grants-2003_04 |
| ORD ID | ord-9b1ac4ffe2d2465b8dda713f095b8da7 |
| Quellennotiz | uspto-grants-2003_04 |