HCID 69688073, compound → Carbamic acid,[2-amino-4-methyl-5-(methylpropylamino)phenyl]-,1,1-dimethylethyl ester

HRID 1265566Notes

Reaction equation

HRID 1265566 reaction equation
[C:1]([O:5][C:6](=[O:23])[NH:7][C:8]1[CH:13]=[C:12]([N:14]([CH3:18])[CH2:15][CH2:16][CH3:17])[C:11]([CH3:19])=[CH:10][C:9]=1[N+:20]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Pd]>[C:1]([O:5][C:6](=[O:23])[NH:7][C:8]1[CH:13]=[C:12]([N:14]([CH3:18])[CH2:15][CH2:16][CH3:17])[C:11]([CH3:19])=[CH:10][C:9]=1[NH2:20])([CH3:2])([CH3:3])[CH3:4]

Participants

3

Reactant 1

HCID 69688073HCID 69688073, compound

Product 1

HCID 69688441Carbamic acid,[2-amino-4-methyl-5-(methylpropylamino)phenyl]-,1,1-dimethylethyl ester

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

The title compound was prepared from [4-methyl-5-(methyl-propyl-amino)-2-nitro-phenyl]-carbamic acid tert-butyl ester (Example C21) (3.59 g, 11.1 mmol) by hydrogenation with 10% Pd/C according to the general procedure J (method a). Obtained as a purple solid (3.23 g, 99%).

Sources & evidence

ORD record
ord-8193449e71fe4c87bfd1241be569d914
Source dataset
uspto-grants-2003_04
Patent number
US06544985B2

Reaction notes

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