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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1265569Generated: October 27, 2026

Stannous chloride dihydrate → Carbamic acid,[2-amino-4-chloro-5-[methyl(2-methylpropyl)amino]phenyl]-,1,1-dimethylethyl ester

https://huagongshe.com/reaction/1265569

Reaction equation

Participants

RoleNameHCIDCharge
ReactantStannous chloride dihydrateHCID 61436—
ReactantHCID 69489728HCID 69489728—
ProductCarbamic acid,[2-amino-4-chloro-5-[methyl(2-methylpropyl)amino]phenyl]-,1,1-dimethylethyl esterHCID 69487013—

Reaction Steps

The title compound was prepared from [4-chloro-5-(isobutyl-methyl-amino)-2-nitro-phenyl]-carbamic acid tert-butyl ester (Example C24) (5.55 g, 15.5 mmol) by reduction with SnCl2.2H2O according to the general procedure J (method b). Obtained as a pale brown solid (3.98 g, 78%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06544985B2
Source datasetuspto-grants-2003_04
ORD IDord-8c000d1a9a1b43cdb1508401afc447ea
Source noteuspto-grants-2003_04