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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1265579Generated: November 1, 2026

HCID 69486618, compound → Carbamic acid,[2-amino-5-[methyl(1-methylethyl)amino]-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl ester

https://huagongshe.com/reaction/1265579

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 69486618HCID 69486618—
CatalystPalladiumHCID 23938—
ProductCarbamic acid,[2-amino-5-[methyl(1-methylethyl)amino]-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl esterHCID 69486615—

Reaction Steps

The title compound was prepared from [5-(isopropyl-methyl-amino)-2-nitro-4-trifluoromethyl-phenyl]-carbamic acid tert-butyl ester (Example C34) (2.98 g, 7.90 mmol) by hydrogenation with 10% Pd/C according to the general procedure J (method a). Obtained as a orange oil (2.42 g, 88%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06544985B2
Source datasetuspto-grants-2003_04
ORD IDord-5d182aa3f78b4731bfe522b2448debe3
Source noteuspto-grants-2003_04