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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1265594Generated: November 3, 2026

Methyl 3-(1H-pyrazol-1-yl)benzoate → 3-Oxo-3-(3-pyrazol-1-yl-phenyl)-propionic acid tert-butyl ester

https://huagongshe.com/reaction/1265594

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3-(1H-pyrazol-1-yl)benzoateHCID 11171669—
ReactantLithium Tert-butyl AcetateHCID 86586795—
Product3-Oxo-3-(3-pyrazol-1-yl-phenyl)-propionic acid tert-butyl esterHCID 69687557—

Reaction Steps

The title compound was prepared from 3-pyrazol-1-yl-benzoic acid methyl ester [CAS-No. 168618-35-7] by treatment with lithium tert.-butyl acetate according to general procedure K (method b). Obtained as a yellow oil (5.00 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06544985B2
Source datasetuspto-grants-2003_04
ORD IDord-60cd1c5067af4c9b9444f9a48dc51699
Source noteuspto-grants-2003_04