HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(2-Bromo-1,1-dimethoxy-ethyl)-benzoic acid methyl ester → 3-Oxo-3-[3-(2-bromo-1,1-dimethoxy-ethyl)-phenyl]-propionic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(2-Bromo-1,1-dimethoxy-ethyl)-benzoic acid methyl ester | HCID 69688480 | — |
| Reactant | Lithium Tert-butyl Acetate | HCID 86586795 | — |
| Product | 3-Oxo-3-[3-(2-bromo-1,1-dimethoxy-ethyl)-phenyl]-propionic acid tert-butyl ester | HCID 69688717 | — |
Reaction Steps
3-(2-Bromo-1,1-dimethoxy-ethyl)-benzoic acid methyl ester (3.9 g) was treated with lithium tert.-butyl acetate according to the general procedure K (method b) to give 3-oxo-3-[3-(2-bromo-1,1-dimethoxy-ethyl)-phenyl]-propionic acid tert-butyl ester (2.8 g) as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06544985B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-39fe6e7e734249ba9a24696a80add4ea |
| Source note | uspto-grants-2003_04 |