HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(2-Methyl-oxazol-4-yl)-benzoic acid methyl ester → 3-Oxo-3-[3-(2-methyl-oxazol-4-yl)-phenyl]-propionic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(2-Methyl-oxazol-4-yl)-benzoic acid methyl ester | HCID 69687437 | — |
| Reactant | Lithium Tert-butyl Acetate | HCID 86586795 | — |
| Product | 3-Oxo-3-[3-(2-methyl-oxazol-4-yl)-phenyl]-propionic acid tert-butyl ester | HCID 69689209 | — |
Reaction Steps
3-(2-Methyl-oxazol-4-yl)-benzoic acid methyl ester (1.02 g) was treated with lithium tert.-butyl acetate according to the general procedure K (method b) to give crude 3-oxo-3-(3-(2-methyl-oxazol-4-yl)-phenyl]-propionic acid tert -butyl ester (1.50 g) as a pale-yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06544985B2 |
| Source dataset | uspto-grants-2003_04 |
| ORD ID | ord-910a5396d0094940985622dbdf30b8ef |
| Source note | uspto-grants-2003_04 |